Lock: Tennessee (NL) over BALTIMORE: The Titans’ impressive defense forced four turnovers in last week’s win over Minnesota, adding to their league-high 12 turnovers. Not only is Tennessee one of three teams still undefeated, but the Titans have looked to veteran QB Kerry Collins, who replaced an injured Vince Young. So far, Collins has done everything his team has asked of him.

Chicago (-3) over DETROIT: The Lions (0-3) hope a front office shake-up with the firing of team President Matt Millen will produce a win. Though the Bears’ defense has managed to blow both a 14-point lead and a 10-point lead in their Week 2 and 3 games, respectively, Detroit’s offense and defense are not up to par. Chicago QB Kyle Orton threw three touchdowns in the first half against Philadelphia last Sunday, but this week Orton will have to do without Brandon Lloyd, who left last week’s game with a knee injury.

DENVER (-3) over Tampa Bay: Jay Cutler is having quite a season, throwing nine touchdowns in four games. Cutler is also second in the league in completions (102) and passing yards (1,275). Denver has to get back on its feet after a kick in the balls by Kansas City last week.

Buffalo (+1) over ARIZONA: Despite three straight losing seasons, the Bills (4-0) are off to their best start and look for their first playoff appearance since 1999. Buffalo is no stranger to pressure, as the Bills had a fourth-quarter comeback against Oakland, scoring 17 points to erase two nine-point deficits in a 24-23 win, their third consecutive fourth-quarter comeback.